Cell Biology

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Structure of cellular shredders varies according to cell type, study shows

"Miniature shredders" are at work in each cell, disassembling and recycling cell components that are defective or no longer required.

16 Mar 2023

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

Albumedix Ltd, Nottingham, United Kingdom, now part of the global life science group Sartorius, and Heartseed Inc ('Heartseed'), Tokyo, Japan, Tuesday 14th March 2023, announce that Recombumin® is a critical component of Heartseed's HS-001, an investigational cardiac remuscularization cell therapy which has commenced first in human dosing.

From Albumedix Ltd. 16 Mar 2023

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

A team of scientists led by Dr. Kei-ichi TAKATA from the Center for Genomic Integrity within the Institute for Basic Science (IBS), has discovered a new type of DNA repair mechanism that cancer cells use to recover from next-generation cancer radiation therapy.

16 Mar 2023

Study sheds new insight into the dynamics of neural stem cell niche

When it comes to cell types, stem cells have unlimited potential – literally. These self-renewing cells, which are capable of giving rise to any cell type in the body, reside in specialized microenvironments known as niches.

16 Mar 2023

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 5, entitled, "AAV1.NT-3 gene therapy prevents age-related sarcopenia."

16 Mar 2023

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

The gut is home to a cast of microbes that influence health and disease. Some types of microorganisms are thought to contribute to the development of inflammatory conditions, such as inflammatory bowel disease (IBD), but the exact cascade of events that leads from microbes to immune cells to disease remains mysterious.

16 Mar 2023

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

15 Mar 2023

High consumption of common artificial sweetener lowers activation of T-cells in mice

Scientists at the Francis Crick Institute have found that high consumption of a common artificial sweetener, sucralose, lowers activation of T-cells, an important component of the immune system, in mice.

15 Mar 2023

Researchers uncover new clue as to how "whole genome doubling" drives cancer

A single cell contains 2-3 meters of DNA, meaning that the only way to store it is to package it into tight coils.

15 Mar 2023

New biomimetic model helps study wound healing in burn and laceration wounds

Burn wounds are notoriously prone to bacterial infection and typically lead to a larger amount of scar tissue than laceration wounds.

15 Mar 2023

Researchers design a virus-resistant, more useful E. coli bacteria

In a step forward for genetic engineering and synthetic biology, researchers have modified a strain of Escherichia coli bacteria to be immune to natural viral infections while also minimizing the potential for the bacteria or their modified genes to escape into the wild.

15 Mar 2023

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

15 Mar 2023

Newly identified small molecule may help treat people with drug-resistant epilepsy

Researchers at Tufts University School of Medicine and colleagues have identified a small molecule that may help treat people with epilepsy whose condition has become resistant to the benzodiazepine drugs usually used in managing seizures.

15 Mar 2023

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

A new study published in Science Immunology points to a promising therapeutic approach for future cancer treatments based on natural killer cells (NK), which are immune cells that bind to tumor cells and destroy them.

14 Mar 2023

Using antagonistic drug combinations for selective killing of resistant cancer cells

A new review paper was published in Oncotarget's Volume 14 on March 11, 2023, entitled, "Selective protection of normal cells from chemotherapy, while killing drug-resistant cancer cells."

14 Mar 2023

Host immune system forms small lesions in the intestines in response to bacterial infection

Yersinia bacteria cause a variety of human and animal diseases, the most notorious being the plague, caused by Yersinia pestis.

14 Mar 2023

Understanding how cells adjust in real time to withstand stresses on our health

Every minute of every day, our body adapts to meet the needs of each moment. When we binge on carbs, exercise, or become sick, chemical reactions inside our cells switch on, slow down, or shift strategy so that we have the energy and strength we need.

14 Mar 2023

Cell Biology

Structure of cellular shredders varies according to cell type, study shows

Albumedix and Heartseed announce Recombumin® as a critical excipient in the manufacture of Heartseed's HS-001 investigational cell therapy as its first in-human trial commences

Scientists discover mechanism used by cancer cells to repair DNA damage induced by radiotherapy

Study sheds new insight into the dynamics of neural stem cell niche

Study provides strong support for AAV.NT-3 gene therapy in the management of sarcopenia

Purine metabolite xanthine may play a role in Th17 cell differentiation in the gut

Scientists generate 3D ultra-resolution maps of mitochondrial networks in lung tumors

High consumption of common artificial sweetener lowers activation of T-cells in mice

Researchers uncover new clue as to how "whole genome doubling" drives cancer

New biomimetic model helps study wound healing in burn and laceration wounds

Researchers design a virus-resistant, more useful E. coli bacteria

Research reveals the modulatory effect of anti-inflammatory metabolite on immune cells

Newly identified small molecule may help treat people with drug-resistant epilepsy

XBP1s plays a key role in controlling IL-15-mediated NK cell survival, study shows

Using antagonistic drug combinations for selective killing of resistant cancer cells

Host immune system forms small lesions in the intestines in response to bacterial infection

Understanding how cells adjust in real time to withstand stresses on our health

Wayne State team discovers a simple technology to detect active TB infection antibodies

TbID-based proteomic profiling in meiotic cells helps identify proximate proteins in A. thaliana

High-throughput genetic screening approach to study antibiotic proteins made by bacteriophages

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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