Cell Biology

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Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Even though, according to recent preliminary studies, the risk of dying from cancer has declined within the European Union in recent years, cancers remain among the leading causes of death.

13 Mar 2023

Using convolutional neural network to automate the identification of chromatid cohesion defects

Scientists from Tokyo Metropolitan University have used machine learning to automate the identification of defects in sister chromatid cohesion.

13 Mar 2023

New tool allows researchers to perform genetic screens of cell-cell interactions

Inflammatory neurological diseases, such as multiple sclerosis (MS), can arise when cell-to-cell communication between cells in the central nervous system (CNS) goes awry.

13 Mar 2023

Research illuminates the role of ATE1 enzyme in cellular stress response

A new paper in Nature Communications illuminates how a previously poorly understood enzyme works in the cell.

13 Mar 2023

Astrocytes play a key role in motor learning

From steering a car to swinging a tennis racket, we learn to execute all kinds of skilled movements during our lives.

10 Mar 2023

Scientists discover how tendons and salivary glands develop in the jaw

A USC-led team of scientists has made a drool-worthy discovery about how tendons and salivary glands develop in the jaw.

10 Mar 2023

Study creates a radical new view of how immune cells recognize threats

Researchers have created a radical new view of how immune cells recognise threats such as viruses. The discovery could be used to design better vaccines and to gain a deeper insight into autoimmune diseases and allergies.

10 Mar 2023

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

A scientific instrument at the Department of Energy's Oak Ridge National Laboratory could help create a noninvasive cancer treatment derived from a common tropical plant.

10 Mar 2023

Important backup mechanism of human immune cells elucidated

The enzyme TBK1 is an important component of the innate immune system that plays a critical role in the defense against viruses.

10 Mar 2023

Study reveals molecular basis of how CAMSAP3 protein stabilizes microtubules within cells

Like poles support a tent, microtubules - hollow cylindrical structures made of tubulin protein - support eukaryotic cells.

9 Mar 2023

UVA scientists identify a detox approach to delay aging

University of Virginia scientists have identified a promising approach to delay aging by detoxifying the body of glycerol and glyceraldehyde, harmful by-products of fat that naturally accumulate over time.

9 Mar 2023

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Researchers at UT Southwestern Medical Center have discovered how healthy bacteria can escape the intestine, travel to lymph nodes and cancerous tumors elsewhere in the body, and boost the effectiveness of certain immunotherapy drugs.

9 Mar 2023

Newly found protein complex plays a crucial role in messenger RNA stability

Two proteins come together to protect and stabilize RNA as it carries muscle-forming code through the cell. Further understanding this RNA-stabilizing complex may have implications for influencing muscle recovery and disease treatment.

9 Mar 2023

C-reactive protein has a beneficial function in systemic lupus erythematosus

The biological function of the C-reactive protein, CRP, has long been unknown. Researchers at Linköping University in Sweden now show that this protein has a beneficial function in systemic lupus erythematosus, SLE, an inflammatory disease.

9 Mar 2023

Scientists discover how excess oxygen changes a handful of proteins in the cells

When it comes to oxygen, you can have too much of a good thing. Breathing air that contains higher levels of oxygen than the usual 21 percent found in Earth's atmosphere can cause organ damage, seizures, and even death in people and animals, particularly if it's in excess of the body's oxygen needs.

8 Mar 2023

Microglia partner with T cells to cause neurodegeneration, study shows

Nearly two dozen experimental therapies targeting the immune system are in clinical trials for Alzheimer's disease, a reflection of the growing recognition that immune processes play a key role in driving the brain damage that leads to confusion, memory loss and other debilitating symptoms.

8 Mar 2023

Scientists unearth a potential new target for treating age-related neurological diseases

Scientists from the Trinity Biomedical Sciences Institute (TBSI) have shed new light on aging processes in the brain.

8 Mar 2023

Connection between mitochondrial metabolite and activation of inflammatory response revealed

A new study shows for the first time a connection between a mitochondrial metabolite and the activation of an inflammatory response.

8 Mar 2023

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Mass General researchers have discovered a novel molecular mechanism responsible for the most common forms of acquired hydrocephalus, potentially opening the door to the first-ever nonsurgical treatment for a life-threatening disease that affects about a million Americans.

8 Mar 2023

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Research in animal models has demonstrated that stem-cell derived heart tissues have promising potential for therapeutic applications to treat cardiac disease. But before such therapies are viable and safe for use in humans, scientists must first precisely understand on the cellular and molecular levels which factors are necessary for implanted stem-cell derived heart cells to properly grow and integrate in three dimensions within surrounding tissue.

8 Mar 2023

Cell Biology

Components of the gut microbiome could be used to better predict efficacy of CAR-T cell therapy

Using convolutional neural network to automate the identification of chromatid cohesion defects

New tool allows researchers to perform genetic screens of cell-cell interactions

Research illuminates the role of ATE1 enzyme in cellular stress response

Astrocytes play a key role in motor learning

Scientists discover how tendons and salivary glands develop in the jaw

Study creates a radical new view of how immune cells recognize threats

New insights into how spider lily compound kills cancer cells while keeping healthy cells intact

Important backup mechanism of human immune cells elucidated

Study reveals molecular basis of how CAMSAP3 protein stabilizes microtubules within cells

UVA scientists identify a detox approach to delay aging

Healthy gut bacteria can travel to other parts of the body and boost antitumor immunity

Newly found protein complex plays a crucial role in messenger RNA stability

C-reactive protein has a beneficial function in systemic lupus erythematosus

Scientists discover how excess oxygen changes a handful of proteins in the cells

Microglia partner with T cells to cause neurodegeneration, study shows

Scientists unearth a potential new target for treating age-related neurological diseases

Connection between mitochondrial metabolite and activation of inflammatory response revealed

Novel molecular mechanism responsible for common form of acquired hydrocephalus discovered

Using tissue-embedded nanoelectronic devices to monitor the functional maturation of cardiomyocytes

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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