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O-linked sialoglycans affect SARS-CoV-2 spike cleavage

In a recent study posted to the bioRxiv* preprint server, researchers from Spain, the United Kingdom, and the United States used chemical tools to uncover the molecular details of glycan-mediated modulation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) processing.

19 Sep 2022

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

The wastewater environmental surveillance conducted in Jerusalem, Israel, has detected an increasing population of poliovirus type 2. Furthermore, these viral isolates are associated with vaccine-derived viral strains.

19 Sep 2022

The predominant lineage in Europe of gonococcus is resistant to one of common drug treatments

A study featuring the participation of Fisabio (Foundation for the Promotion of Health and Biomedical Research of Valencia Region), dependent on the Conselleria de Sanitat Universal i Salut Pública, has found that the predominant lineage in Europe of gonococcus—the bacterium which causes gonorrhea—is resistant to one of the two drugs, among others, most commonly used today to treat this disease.

19 Sep 2022

United States joins 30 other countries with circulating vaccine-derived poliovirus

CDC today announced that polioviruses found in New York, both from the case of paralytic polio in an unvaccinated adult in Rockland County and in several wastewater samples from communities near the patient's residence, meet the World Health Organization (WHO)'s criteria for circulating vaccine-derived poliovirus (cVDPV) – meaning that poliovirus continues to be transmitted in Rockland County, NY, and surrounding areas.

19 Sep 2022

Pilot program intends to address inequities in accessing monkeypox vaccines

Today, local, state, and territorial health departments, as well as tribal governments and local non-governmental organizations, can partner together and begin submitting requests to access monkeypox vaccine through the recently announced Monkeypox Vaccine Equity Pilot Program.

19 Sep 2022

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

Researchers compared in-hospital mortality across COVID-19 pandemic periods.

19 Sep 2022

The relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samples

Researchers investigated how antigen concentration and viral load in different specimen types affected the performance of SARS-CoV-2 rapid diagnostic tests (RDTs).

19 Sep 2022

Better infectious disease surveillance system needed in Canada to detect respiratory pathogens

Canada needs a better infectious disease surveillance system to detect emerging respiratory pathogens that includes waste-water testing, population-based testing and genomics, according to an analysis published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.220577.

19 Sep 2022

Native Hawaiians/Pacific Islanders deeply affected by the COVID-19 pandemic, studies report

Native Hawaiians/Pacific Islanders, or NH/PIs, comprising more than 20 ethnic groups hailing from Polynesia, Micronesia, and Melanesia, are understudied despite being the third fastest growing racial group in the United States. Two studies now report that NH/PIs have been deeply affected by the COVID-19 pandemic.

19 Sep 2022

The maternal and perinatal outcomes of pregnancies complicated by monkeypox infection

Researchers evaluated the perinatal and maternal outcomes of pregnancies complicated by infection with the monkeypox virus.

19 Sep 2022

Monkeypox virus infection in an immunocompromised patient

Researchers assessed the manifestations of the monkeypox infection in an immunocompromised patient.

19 Sep 2022

The potential for measles and rubella elimination globally

Researchers modeled the probability of eradication of measles and rubella by 2100.

19 Sep 2022

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Researchers assessed the impact of SARS-CoV-2 vaccines on human fertility.

19 Sep 2022

Is aspirin linked to higher rates of survival for cancer patients?

Researchers discussed the existing evidence on the use of acetylsalicylic acid (aspirin) in cancer treatment.

19 Sep 2022

Monkeypox could spread everywhere, if neglected

A new article published in the journal Science by Nigerian scientists provides perspective on the consequences of neglecting a disease, anywhere, such as Monkeypox.

19 Sep 2022

Vaccines used to prevent monkeypox

A new review published in The Lancet Infectious Diseases aimed to describe the efficacy of vaccinia virus-based smallpox vaccines against the current monkeypox outbreak.

18 Sep 2022

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

In a recent study posted to the bioRxiv* server, researchers at the United States Army Medical Research Institute of Infectious Diseases evaluated the immunogenicity of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) deoxyribonucleic acid (DNA) vaccine, nCOV-S(JET), in rhesus macaques

18 Sep 2022

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

In a recent study posted to the bioRxiv* preprint server, researchers in the United States assessed the role of two cytokines, interferon-gamma (IFN-γ) and interleukin-10 (IL-10), in regulating immune cell responses and inflammation early during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in rhesus macaques.

18 Sep 2022

An improved COVID-19 vaccine shows promise against Omicron in experimental models

In a recent study published in the journal Science Translational Medicine, researchers in the United States designed a bivalent coronavirus disease 2019 (COVID-19) vaccine on the messenger ribonucleic acid (mRNA) platform.

18 Sep 2022

COVID-19 increases risk of developing Alzheimer's by 50-80% in older adults

In a recent study published in the Journal of Alzheimer’s Disease, researchers investigated whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections could trigger the development of new-onset Alzheimer’s disease (AD)

18 Sep 2022

Disease/Infection News

O-linked sialoglycans affect SARS-CoV-2 spike cleavage

Environmental surveillance detects poliovirus type 2 outbreaks in Israel

The predominant lineage in Europe of gonococcus is resistant to one of common drug treatments

United States joins 30 other countries with circulating vaccine-derived poliovirus

Pilot program intends to address inequities in accessing monkeypox vaccines

Comparative hospitalization and mortality risk in the US population during the Omicron and Delta periods

The relationship between antigen concentration and diagnostic test performance for SARS-CoV-2 on different types of samples

Better infectious disease surveillance system needed in Canada to detect respiratory pathogens

Native Hawaiians/Pacific Islanders deeply affected by the COVID-19 pandemic, studies report

The maternal and perinatal outcomes of pregnancies complicated by monkeypox infection

Monkeypox virus infection in an immunocompromised patient

The potential for measles and rubella elimination globally

Is there any impact of COVID-19 vaccines on the fertility of men and women of reproductive age?

Is aspirin linked to higher rates of survival for cancer patients?

Monkeypox could spread everywhere, if neglected

Vaccines used to prevent monkeypox

Needle-free jet injection of novel COVID-19 DNA vaccine shows promise in animal model

Research examines the roles of cytokines during SARS-CoV-2 infection in rhesus macaques

An improved COVID-19 vaccine shows promise against Omicron in experimental models

COVID-19 increases risk of developing Alzheimer's by 50-80% in older adults

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