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Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Researchers at the AIDS Institute, The University of Hong Kong, Department of Microbiology, School of Clinical Medicine, the LKS Faculty of Medicine of The University of Hong Kong and the State Key Laboratory of Emerging Infectious Diseases, HKU, together with structural biologists at The Hong Kong University of Science and Technology, have demonstrated that ZCB11, a broadly neutralizing antibody derived from a local mRNA-vaccinee against the spreading Omicron variants of SARS-CoV-2, displays potent antiviral activities against all variants of concern (VOCs), including the dominantly spreading Omicron BA.1, BA1.1 and BA.2.

13 Jul 2022

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

In a new study, researchers reported that Pfizer’s BNT162b2 vaccine against severe acute respiratory syndrome coronavirus 2 does not affect the honeymoon phase of type 1 diabetes (T1D).

13 Jul 2022

The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients

Scientists assessed the potential of tixagevimab–cilgavimab for treating hospitalized SARS-CoV-2 patients.

13 Jul 2022

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

Researchers assessed the efficacy of the novel SARS-CoV-2 doggybone deoxyribonucleic acid (DNA) vaccine.

13 Jul 2022

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

Researchers analyzed the structural function of the genetic background of SARS-CoV-2 in the appearance and persistence of A222V spike mutation.

13 Jul 2022

Does high-dose inhaled nitric oxide improve respiratory function and outcomes among pregnant patients hospitalized with severe COVID-19 pneumonia?

Researchers demonstrated that inhaled nitric oxide 200 (iNO200) enhances oxygenation in pregnant COVID-19 patients with severe pneumonia.

13 Jul 2022

How has the COVID-19 pandemic impacted prescribing pancreatic enzyme replacement to people with unresectable pancreatic cancer?

Researchers evaluated the impact of the COVID-19 pandemic on the rates of pancreatic enzyme replacement therapy (PERT) prescribing in England.

13 Jul 2022

A large, observational, household-based, remote cohort study of SARS-CoV-2 infection and transmission in households with children

Researchers designed a cohort-based surveillance study to identify risk factors for SARS-CoV-2 infection and its household transmission among children and individuals with asthma and allergic diseases.

13 Jul 2022

Immunoglobulin G isotypes switch class following repeated SARS-CoV-2 mRNA vaccination

Researchers reported a class switch in SARS-CoV-2-specific antibodies due to repeated mRNA vaccinations.

13 Jul 2022

Study suggests vaping does not increase risk of COVID-19

Researchers examine the risk of PCR-confirmed COVID-19 with the use of e-cigarettes.

12 Jul 2022

Production of anti-SARS-CoV-2 antibodies from hyperimmunized chickens

A new study reports the production of neutralizing antibodies against SARS-CoV-2 in hyperimmunized hens.

12 Jul 2022

Detection of SARS-CoV-2 variants in aircraft wastewater

Researchers detect SARS-CoV-2 variants in the wastewater of aircrafts

12 Jul 2022

How common is pediatric cannabis use and what are the risks?

New research evaluated the recent usage of marijuana and its derivative products, their effects and clinical manifestations, perceptions, pharmaceutics, epidemiological studies, and the long-term ramifications in pediatric populations.

12 Jul 2022

Scientists explore antigenic imprinting in SARS-CoV-2

A recently published study compared monoclonal RBD antibody responses induced by SARS-CoV-2 Beta variant infections to antibodies induced by the ancestral virus in immunologically naive subjects.

12 Jul 2022

University of Oxford begins recruiting for Phase I trial of new TB vaccine

The University of Oxford has begun recruiting for a Phase I trial with a tuberculosis vaccine in human volunteers at Oxford to develop a new way to test the efficacy of future TB vaccines - with the first volunteers being challenged today (Wednesday).

12 Jul 2022

Scientists determine the binding affinity of anti-SARS-CoV-2 antibodies in response to infection or vaccination

Scientists measured the quantity and binding affinity (avidity) of antibodies against five different viral proteins.

12 Jul 2022

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Researchers assessed the impact of the vaccinia virus vaccine on the immune response against the monkeypox virus.

12 Jul 2022

Does COVID-19 cause hair loss?

A new study discusses hair loss as a result of COVID-19.

12 Jul 2022

Hospital-acquired pneumonia is killing patients. Yet there is a simple way to stop it.

Four years ago, when Karen Giuliano went to a Boston hospital for hip replacement surgery, she was given a pale-pink bucket of toiletries issued to patients in many hospitals.

12 Jul 2022

How do symptom burden and viral kinetics differ between healthy, vaccinated adults infected with either Delta, Omicron BA.1, or BA.2?

Researchers assessed the symptom profiles present in SARS-CoV-2 Delta, Omicron BA1. and BA.2-infected patients.

12 Jul 2022

Disease/Infection News

Study suggests ZCB11 as a promising antibody drug against all SARS-CoV-2 variants of concern

Pfizer’s SARS-CoV-2 vaccine does not affect the honeymoon phase of type 1 diabetes

The potential of tixagevimab–cilgavimab for treating hospitalized COVID-19 patients

Doggybone DNA COVID-19 vaccine can effectively neutralize SARS-CoV-2 variants

The impact of the SARS-CoV-2 spike A222V mutation on viral infection

Does high-dose inhaled nitric oxide improve respiratory function and outcomes among pregnant patients hospitalized with severe COVID-19 pneumonia?

How has the COVID-19 pandemic impacted prescribing pancreatic enzyme replacement to people with unresectable pancreatic cancer?

A large, observational, household-based, remote cohort study of SARS-CoV-2 infection and transmission in households with children

Immunoglobulin G isotypes switch class following repeated SARS-CoV-2 mRNA vaccination

Study suggests vaping does not increase risk of COVID-19

Production of anti-SARS-CoV-2 antibodies from hyperimmunized chickens

Detection of SARS-CoV-2 variants in aircraft wastewater

How common is pediatric cannabis use and what are the risks?

Scientists explore antigenic imprinting in SARS-CoV-2

University of Oxford begins recruiting for Phase I trial of new TB vaccine

Scientists determine the binding affinity of anti-SARS-CoV-2 antibodies in response to infection or vaccination

How may the genetic differences observed in the current monkeypox virus outbreak impact immune responses induced by VACV vaccines?

Does COVID-19 cause hair loss?

Hospital-acquired pneumonia is killing patients. Yet there is a simple way to stop it.

How do symptom burden and viral kinetics differ between healthy, vaccinated adults infected with either Delta, Omicron BA.1, or BA.2?

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