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Study identifies new mechanism linking activation of key heart enzyme and oxidative stress

A study, led by University of Iowa researchers, reveals a new dimension for a key heart enzyme and sheds light on an important biological pathway involved in cell death in heart disease.

1 May 2008

Harmful blood glucose levels linked to genetic mutation

A genetic mutation that can raise the amount of glucose in a person's blood to harmful levels is identified today in a study in the journal Science.

1 May 2008

Poor nighttime sleep associated with daytime napping in older adults

Deficiencies in nighttime sleep are associated with daytime napping in older adults, according to a study published in the May 1 issue of the journal SLEEP.

1 May 2008

Antidepressant amitriptyline shown to alleviate symptoms of irritable bowel syndrome

Researchers at Mattel Children's Hospital UCLA have found that low-dose antidepressant therapy can significantly improve the overall quality of life for adolescents suffering from irritable bowel syndrome (IBS).

1 May 2008

Short and long sleepers more likely to have metabolic syndrome

A study published in the May 1 issue of the journal SLEEP is the first known to report that short and long sleepers are more likely to have metabolic syndrome, or a combination of medical disorders that increase the risk of developing cardiovascular disease.

1 May 2008

Phase of clock gene expression in human leukocytes correlates with habitual sleep timing

The phase of clock gene expression in leukocytes, assessed in the absence of the masking effects of light-dark and sleep-wake cycles, correlates with habitual sleep timing, according to a study published in the May 1 issue of the journal SLEEP.

1 May 2008

Obesity and heart failure risk

Heart specialists at Johns Hopkins and elsewhere report what is believed to be the first wide-scale evidence linking severe overweight to prolonged inflammation of heart tissue and the subsequent damage leading to failure of the body's blood-pumping organ.

1 May 2008

New study raises questions about prostate cancer therapies targeting insulin-like growth factor receptor

Therapies under development to treat prostate cancer by inhibiting the ability of insulin-like growth factor (IGF-1) to activate its target receptor could have unexpected results especially if a major tumor suppressor gene - p53 - is already compromised, according to new research by investigators at Fred Hutchinson Cancer Research Center.

1 May 2008

TV injury coverage lacking, study finds

Nearly every night, on nearly every TV station in the country, the local newscast features news of the day's car crashes, fires and other injury-causing events.

1 May 2008

Alendronate may improve successful implantation of maxillary bone

A new study has established that estrogen deficiency negatively affects implant osseointegration in rats' maxillary bone.

1 May 2008

High blood pressure still sneaking past doctors, Stanford study shows

Despite the well-known dangers of high blood pressure, major shortfalls still exist in the screening, treatment and control of the disease even when patients are getting a doctor's care, according to a study from the Stanford University School of Medicine.

1 May 2008

Dual treatment of incontinence and dementia associated with functional decline

Older nursing home residents who took medications for dementia and incontinence at the same time had a 50 percent faster decline in function than those who were being treated only for dementia, according to a study from researchers at Wake Forest University School of Medicine and colleagues.

1 May 2008

Cocaine addicts who use other substances have more mental health problems

A study carried out by Spanish scientists shows that cocaine users who take other addictive substances demonstrate a higher risk of mental health problems.

1 May 2008

Biomarker predicts malignancy potential of HG-PIN lesions in the prostate

Men whose prostate cancer screenings show high grade prostatic intraepithelial neoplasia (HG-PIN) may find themselves in limbo, "stuck" between diagnoses - they are told prostate cancer has not yet developed, but it might, and they are advised to undergo repeated needle biopsies as a precaution.

1 May 2008

Obesity can worsen the impact of asthma

Obesity can worsen the impact of asthma and may also mask its severity in standard tests, according to researchers in New Zealand, who studied lung function in asthmatic women with a range of body mass indexes (BMIs).

1 May 2008

Study raises questions about prostate cancer therapies targeting IGF-1

1 May 2008

New discoveries in hearing health

Three studies published in the May 2008 edition of Otolaryngology - Head and Neck Surgery reveal substantial new findings in several areas of hearing health, including research that indicates that patients with profound hearing loss benefit substantially from having cochlear implants placed in both ears, rather than one, as is the common practice.

1 May 2008