Gene News and Research

Latest Gene News and Research

Two new compounds can block cancer cell’s escape route

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.

27 Jul 2023

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

A gene encoding a protein linked to tau production - tripartite motif protein 11 (TRIM11) - was found to suppress deterioration in small animal models of neurodegenerative diseases similar to Alzheimer's disease (AD), while improving cognitive and motor abilities, according to new research from the Perelman School of Medicine at the University of Pennsylvania.

27 Jul 2023

New gene editing approach could revolutionize the treatment of blood disorders

In a step forward in the development of genetic medicines, researchers at Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania have developed a proof-of-concept model for delivering gene editing tools to treat blood disorders, allowing for the modification of diseased blood cells directly within the body.

27 Jul 2023

MU researcher receives $3 million grant to use gene editing for investigating the building blocks of disease

In a new study funded by a $3 million grant from the National Institutes of Health (NIH), University of Missouri researcher Kiho Lee, an associate professor in the College of Agriculture, Food and Natural Resources, will use gene editing to investigate the building blocks of disease.

27 Jul 2023

How MGI boosts agrigenomics and food sustainability with sequencing technology: an Australian case study

In the wake of the recent UN Food Systems +2 Stocktaking Moment in Rome, the spotlight on global food security has never been more critical. Addressing the challenges of a burgeoning population and changing climate requires innovative solutions, and one area showing remarkable promise is agrigenomics.

From MGI 27 Jul 2023

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Sequencing technology is playing an increasingly important role in agriculture, including crops, livestock and poultry, aquatic organisms, and more.

From MGI 27 Jul 2023

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Esophageal adenocarcinoma (EAC) is a highly lethal cancer, with a five-year survival rate of less than 20 percent. Although a precursor lesion to EAC, called Barrett's esophagus (BE), is present in roughly seven percent of middle-aged adults, less than one percent of BE patients will progress to EAC, making it difficult to determine which individuals are at risk of developing this deadly cancer.

27 Jul 2023

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

A team led by researchers at Massachusetts General Hospital (MGH) has discovered a protein that plays critical roles in alerting the body to a bacterial infection and initiating an effective immune response to fight back against the invasion.

27 Jul 2023

People with Alzheimer's risk gene may lose ability to detect odors earlier

People who carry the gene variant associated with the strongest risk for Alzheimer's disease may lose their ability to detect odors earlier than people who do not carry the gene variant, which may be an early sign of future memory and thinking problems, according to a study published in the July 26, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

26 Jul 2023

Core promoter variation may drive development of triple-negative breast cancer

TNBC is a particularly aggressive subtype of breast cancer, characterized by the absence of three key receptors: estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2).

26 Jul 2023

Scientists unravel step-by-step activation process of protein with deep evolutionary history

Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.

26 Jul 2023

Mealworm protein slows weight gain and improves metabolic health in mice

As the global population grows under a changing climate, the urgency to find sustainable protein sources is greater than ever. Plant-based "meat" and "dairy" products may be popular, but they're not the only environmentally friendly meat alternatives.

26 Jul 2023

Researchers create "synthetic embryos" from bovine pluripotent stem cells

An article published in the journal Cell Stem Cell describes the first scientific study to develop blastoids – "synthetic embryos", as they were initially (and incorrectly) called – from bovine pluripotent stem cells (PSCs).

26 Jul 2023

Researchers discover potential new treatment for rhabdomyosarcoma

Researchers from the Leibniz Institute on Aging in Jena and the Brandenburg University of Technology Cottbus-Senftenberg have discovered a novel treatment approach for soft tissue tumors, which are frequently occurring in children and are often malignant.

26 Jul 2023

Study identifies specific genetic variants that affect the skeletal form and ties a major evolutionary facet of human anatomical change to pathogenesis

Researchers evaluate imaging information and characterize skeletal proportions to assess the genetic root of these traits and their connections to each other.

26 Jul 2023

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

The study described in Scientific Reports highlights an impaired response to the hormone progesterone (P4) in cervical fibroblasts from patients with refractory cervical insufficiency (CI).

26 Jul 2023

Tumor-derived GDF-15 suppresses immunotherapy response

Researchers evaluate the impact of tumor-derived GDF-15 on responses to anti-PD-1 immunotherapy.

26 Jul 2023

Positive experiences can reverse cognitive decline in old age

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "MSK1 is required for the beneficial synaptic and cognitive effects of enriched experience across the lifespan."

26 Jul 2023

Japanese researchers identify genetic quirk linked to severe COVID-19

Despite intensive research since the pandemic began, much remains unknown about COVID-19, particularly why it can be so severe in some cases and relatively mild in others.

25 Jul 2023

Primary cilia play a critical role in growth plate regeneration

Growth plates (GP), situated at the ends of long bones in children, supply chondrocytes necessary for bone growth.

25 Jul 2023

Gene News and Research

Latest Gene News and Research

Two new compounds can block cancer cell’s escape route

Penn Medicine researchers identify new therapeutic target for Alzheimer's disease

New gene editing approach could revolutionize the treatment of blood disorders

MU researcher receives $3 million grant to use gene editing for investigating the building blocks of disease

How MGI boosts agrigenomics and food sustainability with sequencing technology: an Australian case study

How do De novo sequencing, QTL mapping, WGS, and lcWGS empower breakthroughs in agrigenomics

Universal genetic testing may improve risk stratification and treatment for rare and lethal cancer

Researchers discover a protein that plays critical roles in alerting the body to a bacterial infection

People with Alzheimer's risk gene may lose ability to detect odors earlier

Core promoter variation may drive development of triple-negative breast cancer

Scientists unravel step-by-step activation process of protein with deep evolutionary history

Mealworm protein slows weight gain and improves metabolic health in mice

Researchers create "synthetic embryos" from bovine pluripotent stem cells

Researchers discover potential new treatment for rhabdomyosarcoma

Study identifies specific genetic variants that affect the skeletal form and ties a major evolutionary facet of human anatomical change to pathogenesis

Cervical fibroblasts in cervical insufficiency patients show impaired responses to progesterone

Tumor-derived GDF-15 suppresses immunotherapy response

Positive experiences can reverse cognitive decline in old age

Japanese researchers identify genetic quirk linked to severe COVID-19

Primary cilia play a critical role in growth plate regeneration

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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