Gene News and Research

Latest Gene News and Research

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

Patients with a type of breast cancer called HER2-positive are less likely to survive if their initial treatment fails to eradicate the tumor completely and they have high levels of immune cells called tumor-infiltrating lymphocytes in the residual disease.

21 Nov 2022

The role of bacteria in cancer growth

Tumor-associated microbiota is an important component of the tumor microenvironment (TME) across 33 types of human cancer. However, little evidence is available regarding the spatial distribution and localization of these microbes in tumor cells.

20 Nov 2022

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

A Ludwig Cancer Research study has revealed a single protein expressed at high levels by cancer cells across a broad range of malignancies that erects a multifaceted barrier to anti-cancer immune responses in mouse models of cancer and so shields tumors from immune detection and destruction.

20 Nov 2022

New gene classifier can predict the risk of cancer cells recurring or progressing

A team of researchers mapping a molecular atlas for ductal carcinoma in situ (DCIS) has made a major advance toward distinguishing whether the early pre-cancers in the breast will develop into invasive cancers or remain stable.

20 Nov 2022

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Researchers detected a swine influenza A virus (IAV)-infected patient in routine surveillance at the National Influenza Center in Denmark. The detected influenza variant appeared distinct from any variant found previously in Denmark.

18 Nov 2022

Scientists explore bat sarbecovirus isolation in Japan

Researchers performed bat sarbecovirus isolation experiments using Rhinolophus cornutus bats from several regions in Japan that were phylogenetically situated in the same cluster of viruses related to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

18 Nov 2022

Bombali ebolavirus has been detected among bats in Mozambique

Researchers reported on the detection of Bombali virus (BOMV, of the ebolavirus genus) ribonucleic acid (RNA) among three free-tailed Mops condylurus (Molossidae) bat species in Mozambique.

18 Nov 2022

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Scientists have developed a clinical WGS workflow that can detect transmission events of a pathogen before they become dominant.

18 Nov 2022

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

In a recent study published in the journal Cell Reports, researchers in Cincinnati, USA, assessed the impact of dietary alteration to a high-fat diet (HFD) on the intestine.

17 Nov 2022

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Researchers examined the prevalence of contraindications to nirmatrelvir-ritonavir (Paxlovid) in hospitalized coronavirus disease 2019 (COVID-19) patients.

17 Nov 2022

Mitochondria plays an important role in signal transduction in innate immune pathways

Mitochondria are primarily known as the powerhouse of the cell. However, these cellular organelles are required not only for providing energy: Professor Konstanze Winklhofer and her group at the Faculty of Medicine at Ruhr University Bochum, Germany, recently discovered that mitochondria play an important role in signal transduction in innate immune pathways.

17 Nov 2022

Scientific gathering aims to integrate advances in cancer and aging research

Institute for Research in Biomedicine - IRB Ageing is the main risk factor for the development of cancer, and the features shared by these two biological processes are increasingly evident. This week the Institute for Research in Biomedicine (IRB Barcelona) and the BBVA Foundation are holding the 38th Barcelona Biomed conference "Quantitative dynamics of aging and premalignancy". Held at the Sant Pau Art Nouveau Site on 14, 15 and 16 November, the event will be hosting 21 internationally recognized experts in the field who will present their latest breakthroughs.

17 Nov 2022

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

Researchers presented a functional analysis of the SARS-CoV-2 open reading frame 3c (ORF3c) protein.

17 Nov 2022

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Researchers characterized the expression of IFN-1 and IFN-2, ISGs, and NF-κB in the upper respiratory tracts of patients with mild and severe COVID-19, to understand innate immune responses to SARS-CoV-2 infections.

17 Nov 2022

Study uncovers new rules for lineage progression

The hypothalamus, one of the most complex brain regions in the mammalian nervous system, contains an astonishing heterogeneity of neurons that regulate endocrine, autonomic and behavioral functions. It not only regulates food consumption, water intake, body temperature, circadian rhythm and sleep to maintain the survival of individual organisms, but also controls puberty onset and reproductive behavior to sustain the breeding population.

17 Nov 2022

Research highlights an understudied aspect of Alzheimer’s disease

Memory loss is often the first sign of Alzheimer's disease, followed by confusion and difficulty thinking. These symptoms reflect the typical pattern of worsening damage to brain tissues. Toxic clusters of proteins first concentrate in the temporal lobes of the brain - the memory area - before spreading to parts of the brain important for thinking and planning.

17 Nov 2022

Omicron BA.2 causes more symptoms and a greater disruption to daily life

In a recent study published in the Nature Communications journal, researchers monitored the changing symptom profiles associated with different severe acute respiratory syndrome CoV-2 (SARS-CoV-2) variants, especially Omicron subvariants BA.1 and BA.2.

16 Nov 2022

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

In a recent study posted to the bioRxiv* preprint server, researchers evaluated responses of natural killer (NK) lymphocytes to VACV (vaccinia virus) infections in vivo.

16 Nov 2022

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

A gene recognized as the strongest risk factor for Alzheimer's disease (AD) alters the way cholesterol moves around the brain and as we age, this altered movement likely contributes to loss of learning and memory, a team of researchers from the Icahn School of Medicine at Mount Sinai and the Massachusetts Institute of Technology reports.

16 Nov 2022

Study could form the basis of blood testing for people at high risk of breast cancer

Researchers have found changes in the levels of particular proteins in people's blood up to two years before they were diagnosed with breast cancer.

16 Nov 2022

Gene News and Research

Latest Gene News and Research

Study provides a more accurate tool to stratify patients with HER2-positive breast cancer

The role of bacteria in cancer growth

Study reveals mechanism by which malignant cells shut down anti-cancer immune responses

New gene classifier can predict the risk of cancer cells recurring or progressing

Human case of swine-origin influenza A virus detected in Denmark, according to CDC study

Scientists explore bat sarbecovirus isolation in Japan

Bombali ebolavirus has been detected among bats in Mozambique

Clinical implementation of continuous genomic surveillance to identify, track, and interrupt the transmission of multidrug-resistant pathogenic bacteria

Gut microbiome in mice gets stressed within 24 hours on a high-fat diet

What is the prevalence of contraindications to Paxlovid among hospitalized COVID-19 patients?

Mitochondria plays an important role in signal transduction in innate immune pathways

Scientific gathering aims to integrate advances in cancer and aging research

SARS-CoV-2 open reading frame 3c protein found to be targeted selectively to mitochondria

SARS-CoV-2 RNA levels, IFN-1, ISGs, and NF-κB gene responses within the respiratory tract of mild and severe COVID-19 patients

Study uncovers new rules for lineage progression

Research highlights an understudied aspect of Alzheimer’s disease

Omicron BA.2 causes more symptoms and a greater disruption to daily life

Study of natural killer lymphocytes transcriptionally reprogrammed by vaccinia virus

Key Alzheimer’s gene alters the way cholesterol moves around the brain, research finds

Study could form the basis of blood testing for people at high risk of breast cancer

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