Gene News and Research

Latest Gene News and Research

Genetic variant associated with slimness estimated to be present in almost 60% of the Europeans

How much do genes influence our body weight? For the general population this influence is around 20%, according to studies that in recent years have analyzed the complete genome of tens of thousands of people.

8 Nov 2022

MGI Partners with ALACRiS Theranostics to Open New Customer Experience Center in Germany

MGI, a company committed to building core tools and technology to lead life science, today announced the launch of its new Customer Experience Center (CEC) in Berlin, Germany.

From MGI 8 Nov 2022

Researchers unravel genetic changes in a region that controls the activity of the genome

Scientists have discovered the cause of a rare condition within a part of the genome that has been largely unexplored in medical genetics. A team at the University of Exeter has found genetic changes in a region that controls the activity of the genome, turning on or off genes, and in doing so they have found a key that could unlock other causes of rare conditions.

8 Nov 2022

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

A single IV infusion of NTLA-2001, a novel CRISPR/Cas9-based gene editing therapy, significantly reduced circulating transthyretin (TTR) protein levels in patients with ATTR amyloid cardiomyopathy, a progressive and fatal cause of heart failure, according to late-breaking research presented today at the American Heart Association’s Scientific Sessions 2022.

7 Nov 2022

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Non-compaction cardiomyopathy is a heart condition caused by defects that arise during fetal development and can have diverse health impacts in affected individuals, including sudden cardiac death.

7 Nov 2022

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with response to chemotherapy in medulloblastomas, a highly malignant brain tumor affecting pediatric, adolescent, and young adult populations.

7 Nov 2022

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Researchers used whole genome sequencing to evaluate monkeypox virus samples from Washington and Ohio states in the United States and identified 25 samples with open reading frame (ORF)-disrupting mutations.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

MGI Partners with Imperial College London to Establish Overseas Customer Experience Center in the UK

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From MGI 7 Nov 2022

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Researchers reviewed technology advancements that will unlock the promise of biologically targeted messenger ribonucleic acid (mRNA) therapeutics beyond vaccines.

7 Nov 2022

Does the time of day patients receive their COVID-19 vaccinations influence their clinical benefit?

Researchers investigated whether the time of day at which COVID-19 patients receive their SARS-CoV-2 vaccinations influences the vaccine effectiveness.

7 Nov 2022

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

A new study demonstrated transcriptomic dysregulation in the cerebral cortex in autism spectrum disorder (ASD).

7 Nov 2022

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Researchers identified a genetic association signal, via genome-wide association studies, between severe COVID-19 with systemic lupus erythematosus, an autoimmune disease.

7 Nov 2022

Efficacy of booster messenger ribonucleic acid COVID-19 vaccinations against SARS-CoV-2 Omicron variant severity

Researchers estimated the effectiveness of monovalent messenger ribonucleic acid (mRNA) coronavirus disease 2019 (COVID-19) vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) infection severity outcomes among adults.

4 Nov 2022

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

In this interview, Niall Dinwoodie, Executive Director for Gene Therapy for Charles River in Europe discusses the opening of their new HQ Plasmid Center of Excellence at Alderley Park.

From Charles Rivers Laboratories Cell and Gene Therapy 4 Nov 2022

Study evaluates BA.5-bivalent booster against new Omicron sublineages

In a new study, researchers evaluated the efficacy of four doses of parental messenger ribonucleic acid (mRNA) vaccine and a BA.5-bivalent booster against recently emerged Omicron sublineages. Additionally, they determined whether prior infection improved the effect of a booster vaccination.

4 Nov 2022

Environmental toxicants contribute to obesity and metabolic disease

In a recent study published in the Current Opinion in Pharmacology journal, researchers assessed the impact of environmental toxicants and brown adipose tissue (BAT) on obesity and metabolic disorders.

4 Nov 2022

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

In a recent study published in the journal Free Radical Biology and Medicine, researchers screened for neuroprotective compounds against Alzheimer’s disease (AD).

3 Nov 2022

Circadian disruption induces weight gain through changes in gut microbiota

In a recent study published in the journal Molecular Metabolism, researchers investigated the impact of environmental and genetic disruptions of the circadian rhythms on the peripheral circadian clock synchronization and microbiome oscillations in the gastrointestinal tract.

3 Nov 2022

Scientists illuminate the molecular events underlying childhood movement disorder

Scientists at the UNC School of Medicine and UNC Eshelman School of Pharmacy, in collaboration with a team from Queen Mary University of London, have illuminated the molecular events underlying an inherited movement and neurodegenerative disorder known as ARSACS – Autosomal recessive spastic ataxia of Charlevoix-Saguenay, named for two Quebec valleys where the first cases were found.

3 Nov 2022

Gene News and Research

Latest Gene News and Research

Genetic variant associated with slimness estimated to be present in almost 60% of the Europeans

MGI Partners with ALACRiS Theranostics to Open New Customer Experience Center in Germany

Researchers unravel genetic changes in a region that controls the activity of the genome

Novel gene editing therapy reduces circulating TTR protein levels in patients with ATTR amyloid cardiomyopathy

Study confirms the implication of Mib1 mutations in non-compaction cardiomyopathy

Researchers identify gene expression correlated with response to chemotherapy in medulloblastomas

Viral whole genome study in the United States identifies ORF-disrupting mutations in monkeypox virus

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

MGI Partners with Imperial College London to Establish Overseas Customer Experience Center in the UK

Beyond vaccines: emerging technologies capable of unlocking the promise of biologically targeted mRNA therapeutics

Does the time of day patients receive their COVID-19 vaccinations influence their clinical benefit?

Transcriptomic dysregulation across cerebral cortex in autism spectrum disorder

Shared genetic effects between the autoimmune disease systemic lupus erythematosus and the clinical consequences of COVID-19

Efficacy of booster messenger ribonucleic acid COVID-19 vaccinations against SARS-CoV-2 Omicron variant severity

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

Study evaluates BA.5-bivalent booster against new Omicron sublineages

Environmental toxicants contribute to obesity and metabolic disease

Green tea catechins and resveratrol display neuroprotective properties in Alzheimer's models

Circadian disruption induces weight gain through changes in gut microbiota

Scientists illuminate the molecular events underlying childhood movement disorder

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