T Cell News and Research

Latest T Cell News and Research

Remdesivir metabolite GS-441524 inhibits SARS CoV-2 in mouse model, finds study

This new study titled, "Remdesivir Metabolite GS-441524 Efficiently Inhibits SARS-CoV-2 Infection in Mouse Model," was released online as a preprint on the bioRxiv* server, prior to undergoing the peer-review process.

2 Nov 2020

Estonian researchers provide clues to control the aggressive nature of SARS-CoV-2

Recent study by Estonian researchers in University of Tartu explains how coronavirus is activated before attacking the cell and what could help to impede that.

2 Nov 2020

Study sheds new light on how the immune system remembers viruses

For a person to acquire immunity to a disease, T cells must develop into memory cells after contact with the pathogen.

2 Nov 2020

Global collaboration provides a COVID-19 disease map

A collaboration of researchers from 120 different institutes across 30 countries including France, Germany, Australia, Japan, USA, India, Turkey, Brazil, and Canada initiated an effort to develop a COVID-19 Disease Map - a collection of computational models and diagrams of molecular mechanisms implicated in COVID-19.

2 Nov 2020

SARS-CoV-2 spike D614G variant exhibits enhanced replication and transmissibility

A team of scientists from Switzerland, Germany, and the USA has demonstrated that the S-614G variant can easily bind to the human angiotensin-converting enzyme 2 (ACE2), the cellular gateway of SARS-CoV-2. The variant also showed enhanced replication and transmissibility in animal models.

2 Nov 2020

Study: 1 in 8 patients with cancer have inherited gene mutations

Genetic testing can uncover inherited genetic mutations, and could individualize cancer therapies, improve survival, manage cancer in loved ones and push the boundaries of precision medicine.

2 Nov 2020

New method marks receptor proteins in selected cells

Where in a nerve cell is a certain receptor protein located? Without an answer to this question, it is difficult to draw firm conclusions about the function of this protein.

2 Nov 2020

Two studies find age as a primary factor in melanoma treatment resistance

Age may cause identical cancer cells with the same mutations to behave differently. In animal and laboratory models of melanoma cells, age was a primary factor in treatment response.

2 Nov 2020

Root bacterium could provide a new approach for treatment of Alzheimer's

A bacterium found among the soil close to roots of ginseng plants could provide a new approach for the treatment of Alzheimer's.

2 Nov 2020

Novel MRI contrast agent offers hope for early detection of Alzheimer’s disease

Hong Kong Baptist University scientists have invented a novel contrast agent for magnetic resonance imaging, which enables real-time visualization and detection of the size and number of amyloid-beta in the brain, a main hallmark of Alzheimer’s disease.

2 Nov 2020

Study reveals seven “forms of disease” in COVID-19

In a study recently published in the top journal "Allergy", a team of MedUni Vienna scientists led by immunologist Winfried F. Pickl and allergologist Rudolf Valenta (both from the Center for Pathophysiology, Infectiology and Immunology) showed that there are seven "forms of disease" in COVID-19.

2 Nov 2020

Ethacridine blocks SARS-CoV-2 with a distinct mode of action

Now, researchers from the University of California, San Francisco, and Stanford University, California, USA, reported a safe and potent antiseptic for use in humans named ethacridine, which effectively inhibits SARS-CoV-2 even at very low concentrations of EC50 ~ 0.08 µM. Their work has is published on the preprint server bioRxiv*.

1 Nov 2020

5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro

Researchers tested 5-amino levulinic acid in vitro in human-derived cells and found it prevents severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Because it is safe and ubiquitous in plants and animals, it could be a potential drug against SARS-CoV-2.

1 Nov 2020

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

The same biochemical triggers that spur a "fight or flight" response when we encounter threats may help tumor cells to thrive.

30 Oct 2020

First-of-its-kind synthetic DNA vaccine designed against Powassan virus

Scientists at The Wistar Institute have designed and tested the first-of-its-kind synthetic DNA vaccine against Powassan virus (POWV), targeting portions of the virus envelope protein.

30 Oct 2020

Potential treatment might make tumors more responsive to immunotherapy

Cancer immunotherapies, which empower patients' immune systems to eliminate tumors, are revolutionizing cancer treatment. Many patients respond well to these treatments, sometimes experiencing long-lasting remissions.

30 Oct 2020

Researchers report a novel approach to generate T-cells faster

Adoptively transferred T-cells can prolong survival and sometimes cure patients with advanced solid tumors. While promising, it can take months to generate the necessary T-cells to help these patients. Such slow speed makes this therapy impractical for most patients who need immediate treatment.

30 Oct 2020

Researchers identify new drug candidate with potential to treat COVID-19

Researchers from the University of Kent, the Goethe-University in Frankfurt am Main (Germany), and the Hannover Medical School (Germany) have identified a drug with the potential to provide a treatment for COVID-19.

30 Oct 2020

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

University of Illinois Urbana-Champaign Professor of Molecular and Integrative Physiology Erik Nelson has won a $4.5M Era of Hope Scholar Award from the United States Department of Defense (DoD) Breast Cancer Research Program (BCRP).

30 Oct 2020

Researchers design a light-sensitive inhibitor that can control cell division and cell death

Ludwig-Maximilians-Universitaet (LMU) in Munich researchers have designed a light-sensitive inhibitor that can control cell division and cell death - and provides a promising approach for studies of essential cellular processes and the development of novel tumor therapies.

30 Oct 2020

T Cell News and Research

Latest T Cell News and Research

Remdesivir metabolite GS-441524 inhibits SARS CoV-2 in mouse model, finds study

Estonian researchers provide clues to control the aggressive nature of SARS-CoV-2

Study sheds new light on how the immune system remembers viruses

Global collaboration provides a COVID-19 disease map

SARS-CoV-2 spike D614G variant exhibits enhanced replication and transmissibility

Study: 1 in 8 patients with cancer have inherited gene mutations

New method marks receptor proteins in selected cells

Two studies find age as a primary factor in melanoma treatment resistance

Root bacterium could provide a new approach for treatment of Alzheimer's

Novel MRI contrast agent offers hope for early detection of Alzheimer’s disease

Study reveals seven “forms of disease” in COVID-19

Ethacridine blocks SARS-CoV-2 with a distinct mode of action

5-amino levulinic acid inhibits SARS-CoV-2 infection in vitro

Drug used to control blood pressure may improve cancer patients’ response to immunotherapy

First-of-its-kind synthetic DNA vaccine designed against Powassan virus

Potential treatment might make tumors more responsive to immunotherapy

Researchers report a novel approach to generate T-cells faster

Researchers identify new drug candidate with potential to treat COVID-19

University of Illinois Urbana-Champaign professor wins $4.5 million for breast cancer research and therapy

Researchers design a light-sensitive inhibitor that can control cell division and cell death

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T Cell News and Research

Latest T Cell News and Research

Immunology eBook

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

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