T Cell News and Research

Latest T Cell News and Research

Novel receptor protein may hold promise for treating COVID-19

A novel receptor protein that binds to the SARS-CoV-2 virus and prevents it from entering cells may hold promise for treating COVID-19 and other coronavirus-related diseases, according to research published online Aug. 4 in the journal SCIENCE.

17 Aug 2020

Discovery offers new hope for millions at risk from antibiotic-resistant infections

There is new hope for approximately 700,000 people who die each year from antibiotic resistant infections, with University of Queensland researchers discovering how bacteria share antibiotic-resistance genes.

17 Aug 2020

Mild COVID-19 cases can trigger robust memory T cell responses

Mild cases of coronavirus disease 2019 (COVID-19) can trigger robust memory T cell responses, even in the absence of detectable virus-specific antibody responses, researchers report August 14 in the journal Cell.

17 Aug 2020

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Switching off a molecular "master regulator" may protect the brain from inflammatory damage and neurodegeneration in Parkinson's disease, reports a study published today in Nature Neuroscience.

17 Aug 2020

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

17 Aug 2020

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Unlike living organisms, to avoid extinction, viruses need to hijack living host machineries to generate new viruses.

17 Aug 2020

Study reveals bacteria's secret weapon to evade immune responses

Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.

17 Aug 2020

Study opens new therapeutic avenue for treating glioblastoma tumors

New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma.

17 Aug 2020

Genome analysis helps detect 568 genes that drive cancer

Analysis of the genomes of 28,000 tumors from 66 types of cancer has led to the identification of 568 cancer driver genes

17 Aug 2020

Combination of nanotechnology and genetic engineering for regulating fatal cancer stemness

The development of chemotherapeutic agents with selective anti-cancer activities is increasingly unattractive due to the emergence of resistance, poor targeting of cancer tissues, and subsequent metastasis.

17 Aug 2020

New type of immunotherapy extends survival of mice with triple negative breast tumors

Immunotherapies for cancer - treatments that prime the immune system to attack tumors - are valuable weapons in the anti-cancer arsenal. But some cancers are more difficult to target with this strategy than others.

17 Aug 2020

Standardized guidelines for phage therapy can speed up lifesaving treatment

When clinicians resort to phage therapy for patients who don't respond to antibiotics, the patients are usually very ill and time is of the essence. But the average time for labs to produce therapeutic phages is more than a month.

17 Aug 2020

Scientists claim signs of lasting SARS-CoV-2 immunity

Questions have been raised by many health experts on whether being infected with SARS-CoV-2 brings lasting immunity. Now, scientists have uncovered signs of strong and lasting immunity in people who even had a mild illness of COVID-19.

17 Aug 2020

Coronacept - A trap-and-destroy molecule against SARS-CoV-2

A new study published on the preprint server bioRxiv* in August 2020 reports a novel engineered molecule based on human and other mammalian orthologues of ACE2 fused with the Fc part of the antibody. This molecule interacts more tightly with the viral receptor-binding domain (RBD) to constitute a powerful immunoadhesin that targets the virus for destruction.

17 Aug 2020

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

The current COVID-19 pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to spread and cause disease and death in many countries even today. At present, there is no effective treatment. A recent study published on the preprint server bioRxiv in August 2020 reports the potential of a new class of drugs called CAR NK cells, which could be used off-the-shelf to treat this disease.

17 Aug 2020

Potential inhibitors of SARS-CoV-2 identified

Now, a new study published on the preprint server bioRxiv in August 2020 reports the discovery of two inhibitors of the helicase enzyme, which is essential for viral replication and the most highly conserved non-structural coronavirus (CoV) protein.

16 Aug 2020

ARDS may not be the primary lung iInjury in COVID-19

A new Italian study published on the preprint server medRxiv in August 2020 shows that this may not be an adequate explanation, since ARDS is a nonspecific diagnosis. Instead, they say, antemortem lung biopsy shows a “Covid pattern” of acute lung injury, which could guide the application of therapeutics.

16 Aug 2020

SARS-CoV-2 spike pocket is a putative target for antiviral design

In a methodologically rigorous study, researchers from the University of Oxford have recently shown how the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein harbors a lipid-binding pocket which modulates the stability of the prefusion trimer and provides conformational shielding from antibodies. Their findings are currently freely available on the bioRxiv* preprint server.

16 Aug 2020

New study challenges hypothesis underlying the sensitivity of mammalian auditory system

A new study from the University of Colorado Anschutz Medical Campus challenges a decades-old hypothesis on adaptation, a key feature in how sensory cells of the inner ear (hair cells) detect sound.

15 Aug 2020

COVID-19 virus acts as a 'sponge' to deplete specific host microRNAs

Why is the COVID-19 virus deadly, while many other coronaviruses are fairly innocuous and just cause colds?

15 Aug 2020

T Cell News and Research

Latest T Cell News and Research

Novel receptor protein may hold promise for treating COVID-19

Discovery offers new hope for millions at risk from antibiotic-resistant infections

Mild COVID-19 cases can trigger robust memory T cell responses

Switching off 'master regulator' may protect critical brain cells from Parkinson's-related damage

Multiplication of ecDNA genes present in many cancer types, drives poor patients outcomes

New technique enables real-time observation of influenza A hemagglutinin during viral entry

Study reveals bacteria's secret weapon to evade immune responses

Study opens new therapeutic avenue for treating glioblastoma tumors

Genome analysis helps detect 568 genes that drive cancer

Combination of nanotechnology and genetic engineering for regulating fatal cancer stemness

New type of immunotherapy extends survival of mice with triple negative breast tumors

Standardized guidelines for phage therapy can speed up lifesaving treatment

Scientists claim signs of lasting SARS-CoV-2 immunity

Coronacept - A trap-and-destroy molecule against SARS-CoV-2

Targeting SARS-CoV-2 with off-the-shelf CAR-NK cells

Potential inhibitors of SARS-CoV-2 identified

ARDS may not be the primary lung iInjury in COVID-19

SARS-CoV-2 spike pocket is a putative target for antiviral design

New study challenges hypothesis underlying the sensitivity of mammalian auditory system

COVID-19 virus acts as a 'sponge' to deplete specific host microRNAs

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T Cell News and Research

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