Genetics News and Research

Latest Genetics News and Research

New study identifies crizotinib drug as possible new coating for drug-eluting stents

A new study has identified an FDA approved cancer drug, crizotinib, as a possible new coating for drug-eluting stents. Researchers found that crizotinib in mice helped prevent the narrowing of blood vessels after stenting without affecting the blood vessel lining.

19 Nov 2014

Type 3 interferons and T helper 2 cells: an interview with Grant Gallagher, Managing Director, HUMIGEN

The type 3 interferons - usually called the “lambda” interferons, or “IFNL” - are the most recently identified IFNs. We (myself and Sergei Kotenko) originally identified the receptor and then the three ligands (IFNL1,2,3; very recently a fourth, IFNL4, was discovered); the key paper was published in 2003.

18 Nov 2014

Scientists identify how ADAR1 gene mutation can lead to diseases

Scientists have discovered how a gene mutation can lead to diseases that occur when the immune system attacks the body by mistake.

18 Nov 2014

Study identifies new gene for progressive form of epilepsy

A study led by researchers at University of Helsinki, Finland and Universities of Melbourne and South Australia has identified a new gene for a progressive form of epilepsy. The findings of this international collaborative effort have been published today, 17 November 2014, in Nature Genetics.

18 Nov 2014

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that help explain the diversity of cancer behaviors.

17 Nov 2014

Preterm birth becomes world's number one killer of young children

For the first time in history, the complications of preterm birth outrank all other causes as the world's number one killer of young children.

17 Nov 2014

Understanding the genetic basis of glaucoma

Scientists from the University of Liverpool have sequenced the mitochondrial genome in glaucoma patients to help further understanding into the genetic basis for the disease.

16 Nov 2014

New view on how nerve cells die in Parkinson's disease

Scientists at Trinity College Dublin have made an important breakthrough in our understanding of Parkin - a protein that regulates the repair and replacement of nerve cells within the brain.

16 Nov 2014

A single gene mutation can halve the risk of heart disease

Recent research has shown that inactivation of a single gene reduces the risk of heart attack by 50%.

14 Nov 2014

New mouse model shows how mutated gene impairs neuronal development in individuals with autism

Geneticists at Heidelberg University Hospital's Department of Molecular Human Genetics have used a new mouse model to demonstrate the way a certain genetic mutation is linked to a type of autism in humans and affects brain development and behavior.

14 Nov 2014

Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

A study led by Massachusetts General Hospital (MGH) investigators has identified what appears to be a molecular switch controlling inflammatory processes involved in conditions ranging from muscle atrophy to Alzheimer's disease.

14 Nov 2014

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Rare mutations that shut down a single gene are linked to lower cholesterol levels and a 50 percent reduction in the risk of heart attack, according to new research from Washington University School of Medicine in St. Louis, the Broad Institute at Massachusetts Institute of Technology and Harvard, and other institutions.

14 Nov 2014

Strains of enterotoxigenic E. coli worldwide have similar toxins and virulence factors

The strains of enterotoxigenic Escherichia coli (ETEC) that infect adults and children in Asia, Africa, and the Americas, have notably similar toxins and virulence factors, according to research published ahead of print in the Journal of Bacteriology.

14 Nov 2014

Unique immunochemotherapy approach to treating pancreatic cancer

VCU Massey Cancer Center and VCU Institute of Molecular Medicine researchers discovered a unique approach to treating pancreatic cancer that may be potentially safe and effective. The treatment method involves immunochemotherapy - a combination of chemotherapy and immunotherapy, which uses the patient's own immune system to help fight against disease.

13 Nov 2014

New scientific paper reveals gaps in knowledge about preterm birth

Preterm birth is now the leading cause of death for children under 5 worldwide, and a new scientific paper reveals a startling lack of knowledge about what causes it and how to prevent it.

13 Nov 2014

Crescendo Bioscience to present new data on Vectra DA at ACR Annual Meeting

Crescendo Bioscience, a wholly-owned subsidiary of Myriad Genetics, Inc., today announced that new data on Vectra DA will be featured at the 2014 American College of Rheumatology Annual Meeting, Nov. 15-19, 2014, in Boston, Massachusetts.

12 Nov 2014

Study reveals ETEC bacteria's genetic composition

Enterotoxigenic Escherichia coli (ETEC) bacteria are responsible each year for around 400 million cases of diarrhoea and 400,000 deaths in the world's low- and middle-income countries. Children under the age of five are most affected.

11 Nov 2014

Five simple steps to reduce type-2 diabetes

There are 29 million U.S. adults diagnosed with diabetes and an additional 1 in 3 diagnosed as pre-diabetic. Diabetes is a serious disease which can result in serious health complications including nerve damage, vision loss, heart disease, and kidney failure, to name a few.

11 Nov 2014

FDA accepts Amgen's evolocumab BLA for review

Amgen today announced that the U.S. Food and Drug Administration has accepted for review Amgen's Biologics License Application (BLA) for evolocumab for the treatment of high cholesterol.

11 Nov 2014

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

Regeneron Pharmaceuticals, Inc. and Sanofi today announced positive results from the interim analysis of a dose-ranging Phase 2b study of dupilumab in adult patients with uncontrolled moderate-to-severe asthma. Dupilumab is an investigational therapy blocking IL-4 and IL-13, two cytokines required for the Th2 immune response.

11 Nov 2014

Genetics News and Research

Latest Genetics News and Research

New study identifies crizotinib drug as possible new coating for drug-eluting stents

Type 3 interferons and T helper 2 cells: an interview with Grant Gallagher, Managing Director, HUMIGEN

Scientists identify how ADAR1 gene mutation can lead to diseases

Study identifies new gene for progressive form of epilepsy

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Preterm birth becomes world's number one killer of young children

Understanding the genetic basis of glaucoma

New view on how nerve cells die in Parkinson's disease

A single gene mutation can halve the risk of heart disease

New mouse model shows how mutated gene impairs neuronal development in individuals with autism

Researchers identify molecular switch that controls inflammatory processes in aging-related disorders

Rare gene mutation linked to lower cholesterol levels, reduced risk of heart attack

Strains of enterotoxigenic E. coli worldwide have similar toxins and virulence factors

Unique immunochemotherapy approach to treating pancreatic cancer

New scientific paper reveals gaps in knowledge about preterm birth

Crescendo Bioscience to present new data on Vectra DA at ACR Annual Meeting

Study reveals ETEC bacteria's genetic composition

Five simple steps to reduce type-2 diabetes

FDA accepts Amgen's evolocumab BLA for review

Regeneron, Sanofi report positive results from dupilumab Phase 2b study in patients with asthma

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